1-(3-(Trifluoromethyl)phenyl)piperazine → HCID 86752902, compound

HRID 1956201Notes

Reaction equation

HRID 1956201 reaction equation
C1(O[C:8](=[O:21])[NH:9][C:10]2[C:11]([O:19][CH3:20])=[N:12][C:13]([CH3:18])=[C:14]([CH2:16][CH3:17])[CH:15]=2)C=CC=CC=1.[F:22][C:23]([F:37])([F:36])[C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([N:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:25]=1>>[CH2:16]([C:14]1[CH:15]=[C:10]([NH:9][C:8]([N:33]2[CH2:32][CH2:31][N:30]([C:26]3[CH:25]=[C:24]([C:23]([F:36])([F:37])[F:22])[CH:29]=[CH:28][CH:27]=3)[CH2:35][CH2:34]2)=[O:21])[C:11]([O:19][CH3:20])=[N:12][C:13]=1[CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 42961-(3-(Trifluoromethyl)phenyl)piperazineHCID 19357010Phenyl N-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)carbamate

Product 1

HCID 86752902HCID 86752902, compoundYield 67%

Procedure

Phenyl-N-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)carbamate and 1-(α, α, α-trifluoro-m-tolyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-6659959f7ebe4f66a5f4d7cfa05d0703
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

Loading…