Piperazin-4-ylacetophenone → HCID 18663104, compound

HRID 1956220Notes

Reaction equation

HRID 1956220 reaction equation
C1(O[C:8](=[O:21])[NH:9][C:10]2[C:11]([O:19][CH3:20])=[N:12][C:13]([CH3:18])=[C:14]([CH2:16][CH3:17])[CH:15]=2)C=CC=CC=1.[C:22]([C:25]1[CH:30]=[CH:29][C:28]([N:31]2[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]2)=[CH:27][CH:26]=1)(=[O:24])[CH3:23]>>[CH2:16]([C:14]1[CH:15]=[C:10]([NH:9][C:8]([N:34]2[CH2:33][CH2:32][N:31]([C:28]3[CH:27]=[CH:26][C:25]([C:22](=[O:24])[CH3:23])=[CH:30][CH:29]=3)[CH2:36][CH2:35]2)=[O:21])[C:11]([O:19][CH3:20])=[N:12][C:13]=1[CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 97269Piperazin-4-ylacetophenoneHCID 19357010Phenyl N-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)carbamate

Product 1

HCID 18663104HCID 18663104, compoundYield 67%

Procedure

Phenyl-N-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)carbamate and 1-(4-acetylphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-c6e984436f9f482898e704bcfbe4a50c
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

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