1-(3-Chlorophenyl)piperazine → HCID 18663133, compound

HRID 1956246Notes

Reaction equation

HRID 1956246 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]([NH:12][C:13](=[O:16])[CH2:14]Cl)[C:6]([O:10][CH3:11])=[N:7][C:8]=1[CH3:9])[CH3:2].[Cl:17][C:18]1[CH:19]=[C:20]([N:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[CH:21]=[CH:22][CH:23]=1>>[CH2:1]([C:3]1[CH:4]=[C:5]([NH:12][C:13]([CH2:14][N:27]2[CH2:26][CH2:25][N:24]([C:20]3[CH:21]=[CH:22][CH:23]=[C:18]([Cl:17])[CH:19]=3)[CH2:29][CH2:28]2)=[O:16])[C:6]([O:10][CH3:11])=[N:7][C:8]=1[CH3:9])[CH3:2]

Participants

3

Reactant 2

HCID 13551-(3-Chlorophenyl)piperazineHCID 18663159HCID 18663159, compound

Product 1

HCID 18663133HCID 18663133, compoundYield 68%

Procedure

N-(5-ethyl-2-methoxy-6-methylpyridine -3-yl)chloroacetamide and 1-(3-chlorophenyl)piperazine were reacted by the same way with the example 69 to obtain the titled compound.

Sources & evidence

ORD record
ord-e3e18fa4aead42b69a41024d62fc3977
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

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