4-Methyloxybenzyl chloride → HCID 18663111, compound

HRID 1956248Notes

Reaction equation

HRID 1956248 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]([NH:12][C:13]([N:15]2[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]2)=[O:14])[C:6]([O:10][CH3:11])=[N:7][C:8]=1[CH3:9])[CH3:2].[CH3:21][O:22][C:23]1[CH:30]=[CH:29][C:26]([CH2:27]Cl)=[CH:25][CH:24]=1>>[CH2:1]([C:3]1[CH:4]=[C:5]([NH:12][C:13]([N:15]2[CH2:16][CH2:17][N:18]([CH2:27][C:26]3[CH:29]=[CH:30][C:23]([O:22][CH3:21])=[CH:24][CH:25]=3)[CH2:19][CH2:20]2)=[O:14])[C:6]([O:10][CH3:11])=[N:7][C:8]=1[CH3:9])[CH3:2]

Participants

3

Reactant 2

HCID 699934-Methyloxybenzyl chlorideHCID 18663120HCID 18663120, compound

Product 1

HCID 18663111HCID 18663111, compoundYield 42%

Procedure

1-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)aminocarbonylpiperazine and 4-methoxybenzylchloride were reacted by the same way with the example 72 to obtain the titled compound.

Sources & evidence

ORD record
ord-f3ccf93161284b38842924c343ac27bf
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

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