1-(2-Fluorophenyl)piperazine → HCID 18663029, compound

HRID 1956250Notes

Reaction equation

HRID 1956250 reaction equation
C1(O[C:8](=[O:22])[NH:9][C:10]2[C:11]([O:19][CH2:20][CH3:21])=[N:12][C:13]([CH3:18])=[C:14]([CH2:16][CH3:17])[CH:15]=2)C=CC=CC=1.[F:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[N:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1>>[CH2:20]([O:19][C:11]1[C:10]([NH:9][C:8]([N:33]2[CH2:32][CH2:31][N:30]([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=3[F:23])[CH2:35][CH2:34]2)=[O:22])=[CH:15][C:14]([CH2:16][CH3:17])=[C:13]([CH3:18])[N:12]=1)[CH3:21]

Participants

3

Reactant 2

HCID 705291-(2-Fluorophenyl)piperazineHCID 18663163HCID 18663163, compound

Product 1

HCID 18663029HCID 18663029, compoundYield 87%

Procedure

Phenyl-N-(2-ethoxy-5-ethyl-6-methylpyridin-3-yl)carbamate and 1-(2-fluorophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-13b792b8c2624b31ae3ac30314c5dbaa
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

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