2-Methoxy-5-(piperazin-1-yl)phenol → HCID 18663147, compound

HRID 1956260Notes

Reaction equation

HRID 1956260 reaction equation
C1(O[C:8](=[O:26])[NH:9][C:10]2[C:11]([O:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[N:12][C:13]([CH3:18])=[C:14]([CH2:16][CH3:17])[CH:15]=2)C=CC=CC=1.[OH:27][C:28]1[CH:29]=[C:30]([N:36]2[CH2:41][CH2:40][NH:39][CH2:38][CH2:37]2)[CH:31]=[CH:32][C:33]=1[O:34][CH3:35]>>[CH2:16]([C:14]1[CH:15]=[C:10]([NH:9][C:8]([N:39]2[CH2:38][CH2:37][N:36]([C:30]3[CH:31]=[CH:32][C:33]([O:34][CH3:35])=[C:28]([OH:27])[CH:29]=3)[CH2:41][CH2:40]2)=[O:26])[C:11]([O:19][C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)=[N:12][C:13]=1[CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 186630462-Methoxy-5-(piperazin-1-yl)phenolHCID 18663175HCID 18663175, compound

Product 1

HCID 18663147HCID 18663147, compoundYield 69%

Procedure

Phenyl-N-(5-ethyl-6-methyl-2-phenoxypyridin-3-yl)carbamate and 1-(3-hydroxy-4-methoxyphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-64fe4c1a6d55472ca7d9cafa0ce17a63
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

Loading…