1-(2-Methoxyphenyl)piperazine → HCID 18663034, compound

HRID 1956288Notes

Reaction equation

HRID 1956288 reaction equation
C1(O[C:8](=[O:22])[NH:9][C:10]2[N:11]([O:20][CH3:21])[CH2:12][C:13]3[CH2:14][CH2:15][CH2:16][CH2:17][C:18]=3[CH:19]=2)C=CC=CC=1.[CH3:23][O:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[N:31]1[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]1>>[CH3:21][O:20][N:11]1[C:10]([NH:9][C:8]([N:34]2[CH2:33][CH2:32][N:31]([C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=3[O:24][CH3:23])[CH2:36][CH2:35]2)=[O:22])=[CH:19][C:18]2[CH2:17][CH2:16][CH2:15][CH2:14][C:13]=2[CH2:12]1

Participants

3

Reactant 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 86752906HCID 86752906, compound

Product 1

HCID 18663034HCID 18663034, compoundYield 64%

Procedure

Phenyl-N-(2-methoxy-5,6,7,8-tetrahydroisoquinolin-3-yl)carbamate and 1-(2-methoxyphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-f1ac4b80e5364c07bc80b83e7b968b14
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

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