1-(3-Chlorophenyl)piperazine → HCID 18663035, compound

HRID 1956289Notes

Reaction equation

HRID 1956289 reaction equation
C1(O[C:8](=[O:22])[NH:9][C:10]2[N:11]([O:20][CH3:21])[CH2:12][C:13]3[CH2:14][CH2:15][CH2:16][CH2:17][C:18]=3[CH:19]=2)C=CC=CC=1.[Cl:23][C:24]1[CH:25]=[C:26]([N:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:27]=[CH:28][CH:29]=1>>[CH3:21][O:20][N:11]1[C:10]([NH:9][C:8]([N:33]2[CH2:32][CH2:31][N:30]([C:26]3[CH:27]=[CH:28][CH:29]=[C:24]([Cl:23])[CH:25]=3)[CH2:35][CH2:34]2)=[O:22])=[CH:19][C:18]2[CH2:17][CH2:16][CH2:15][CH2:14][C:13]=2[CH2:12]1

Participants

3

Reactant 2

HCID 13551-(3-Chlorophenyl)piperazineHCID 86752906HCID 86752906, compound

Product 1

HCID 18663035HCID 18663035, compoundYield 69%

Procedure

Phenyl-N-(2-methoxy-5,6,7,8-tetrahydroisoquinolin-3-yl)carbamate and 1-(3-chlorophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-18f0d24b5ce84cd7869825232fbb8bbb
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

Loading…