1-(2-Fluorophenyl)piperazine → HCID 18663033, compound

HRID 1956290Notes

Reaction equation

HRID 1956290 reaction equation
C1(O[C:8](=[O:22])[NH:9][C:10]2[N:11]([O:20][CH3:21])[CH2:12][C:13]3[CH2:14][CH2:15][CH2:16][CH2:17][C:18]=3[CH:19]=2)C=CC=CC=1.[F:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[N:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1>>[CH3:21][O:20][N:11]1[C:10]([NH:9][C:8]([N:33]2[CH2:32][CH2:31][N:30]([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=3[F:23])[CH2:35][CH2:34]2)=[O:22])=[CH:19][C:18]2[CH2:17][CH2:16][CH2:15][CH2:14][C:13]=2[CH2:12]1

Participants

3

Reactant 2

HCID 705291-(2-Fluorophenyl)piperazineHCID 86752906HCID 86752906, compound

Product 1

HCID 18663033HCID 18663033, compoundYield 70%

Procedure

Phenyl-N-(2-methoxy-5,6,7,8-tetrahydroisoquinolin-3-yl)carbamate and 1-(2-fluorophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-2f84a38e2a124e8db3ffa8125e7a6f6a
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

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