1-(2-Fluorophenyl)piperazine → HCID 18663152, compound

HRID 1956293Notes

Reaction equation

HRID 1956293 reaction equation
C1(O[C:8](=[O:22])[NH:9][C:10]2[C:11]([O:20][CH3:21])=[N:12][C:13]([CH3:19])=[C:14]([CH:16]([CH3:18])[CH3:17])[CH:15]=2)C=CC=CC=1.[F:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[N:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1>>[CH:16]([C:14]1[CH:15]=[C:10]([NH:9][C:8]([N:33]2[CH2:32][CH2:31][N:30]([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=3[F:23])[CH2:35][CH2:34]2)=[O:22])[C:11]([O:20][CH3:21])=[N:12][C:13]=1[CH3:19])([CH3:17])[CH3:18]

Participants

3

Reactant 2

HCID 705291-(2-Fluorophenyl)piperazineHCID 18663177HCID 18663177, compound

Product 1

HCID 18663152HCID 18663152, compoundYield 59%

Procedure

Phenyl-N-(5-isopropyl-2-methoxy-6-methylpyridin-3-yl)carbamate and 1-(2-fluorophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-1eb1f5a35d844db48ca921dc258d45ee
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

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