HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl (ethoxymethylene)malonate → Diethyl 6-ethoxy-3-pyridylaminomethylenemalonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | 6-Ethoxypyridin-3-amine | HCID 3040301 | — |
| Product | Diethyl 6-ethoxy-3-pyridylaminomethylenemalonate | HCID 621746 | — |
Reaction Steps
5-Amino-2-ethoxypyridine (9.25 g) and diethyl ethoxymethylenemalonate (14.5 g) was heated at 95° C. for 1 hour. On cooling in ice the oil solidified. The solid was ground up in petroleum ether (b.p. 60°-80° C.) and filtered to give diethyl 2-(6-ethoxy-3-pyridylaminomethylene)malonate, m.p. 68°-71° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780482 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-83571182e5f44bc29b9690f7a75f4de0 |
| Source note | uspto-grants-1998_07 |