HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl (ethoxymethylene)malonate → Diethyl 2-(6-phenoxy-3-pyridylaminomethylene)malonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | 6-Phenoxy-3-pyridinamine | HCID 212856 | — |
| Solvent | Water | HCID 962 | — |
| Product | Diethyl 2-(6-phenoxy-3-pyridylaminomethylene)malonate | HCID 23209163 | — |
Reaction Steps
A mixture of 5-amino-2-phenoxypyridine (10.49 g) and diethyl ethoxymethylenemalonate (12.2 g) was boiled under reflux for 2.5 hours. The mixture was cooled to ambient temperature and water (50 ml) was added. The mixture was extracted with dichloromethane to give diethyl 2-(6-phenoxy-3-pyridylaminomethylene)malonate as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780482 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-61f7a8462a1c407ca11de2861aaafac4 |
| Source note | uspto-grants-1998_07 |