P-Anisidine → HCID 23209243, compound

Participants

Reaction Steps

A mixture of ethyl 4-chloro-6-phenoxy-1,5-naphthyridine-3-carboxylate (3.0 g), 4-methoxyaniline (1.16 g), potassium carbonate (2.65 g) and THF (60 ml) was stirred at ambient temperature for 24 hours. The reaction mixture was worked up as described in Example 2 to give ethyl 4-(4-methoxyanilino)-6-phenoxy-1,5-naphthyridine-3-carboxylate hydrochloride, m.p. 191°-193° C.

Provenance & Evidence