N-Methylpropylamine → HCID 18663621, compound

HRID 1956574Notes

Reaction equation

HRID 1956574 reaction equation
Br[CH2:2][C:3]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[O:7][C:6]2[CH:14]=[CH:15][CH:16]=[C:17]([Cl:18])[C:5]=2[CH:4]=1.[CH3:19][NH:20][CH2:21][CH2:22][CH3:23]>>[ClH:18].[Cl:18][C:17]1[C:5]2[CH:4]=[C:3]([CH2:2][N:20]([CH3:19])[CH2:21][CH2:22][CH3:23])[C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=3[O:7][C:6]=2[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 12315N-MethylpropylamineHCID 18663584HCID 18663584, compound

Product 1

HCID 18663621HCID 18663621, compoundYield 25%

Procedure

Preparation analogous to Example 2 from 10-bromomethyl-1-chlorodibenz[b,f]oxepine with N-methyl-propylamine; yield: 25%; beige solid; melting point: not determined, (beige foam); 1H-NMR (CDCl3, 200 MHz): 0.88 (t, 3H); 1.55 (m, 2H); 2.28 (s, 3H); 2.43 (t, 2H); 3.55 (s, 2H), 7.08-7.35 (m, 7H); 7.61 (d, 1H).

Sources & evidence

ORD record
ord-16e3bf5836524091a22ad15f1be75a76
Source dataset
uspto-grants-1998_07
Patent number
US05780500

Reaction notes

Loading…