HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → Dibenz[b,f]oxepin-10-yl-morpholin-4-yl-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | Dibenzo[b,f]oxepine-10-carboxylic acid | HCID 859640 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | Dibenz[b,f]oxepin-10-yl-morpholin-4-yl-methanone | HCID 18663618 | 62% |
Reaction Steps
Preparation analogous to Example 10a from dibenz[b,f]oxepine-10-carboxylic acid and morpholine; yield: 62%; yellow oil; 1H-NMR (CDCl3, 200 MHz): 3.30 (mbr, 4H); 3.62 (mbr, 4H); 6.90-7.28 (m, 9H); MS: 307 (M+), 221, 193, 165; TLC (silica gel; ethyl acetate/hexane=1:1; UV): Rf =0.17.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780501 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-6e42b42aa8b94444a9772ce2d6104238 |
| Source note | uspto-grants-1998_07 |