HCID 18663613, compound → HCID 18663612, compound

HRID 1956606Notes

Reaction equation

HRID 1956606 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[O:12][C:11]3[CH:13]=[CH:14][CH:15]=[CH:16][C:10]=3[CH:9]=[C:8]([C:17](O)=[O:18])[C:7]=2[CH:20]=1>C(OCC)(=O)C.CCCCCC>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[O:12][C:11]3[CH:13]=[CH:14][CH:15]=[CH:16][C:10]=3[CH:9]=[C:8]([CH2:17][OH:18])[C:7]=2[CH:20]=1

Participants

3

Reactant 1

HCID 18663613HCID 18663613, compound

Product 1

HCID 18663612HCID 18663612, compoundYield 96%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Preparation analogous to Example 12f) from 8-methoxy-dibenz[b,f]oxepine-10-carboxylic acid. Yield: 96% in the form of a brown oil; TLC (silica gel; ethyl acetate/hexane=1:1; UV): Rf =0.31; 1H-NMR (CDCl3, 300 MHz): 1.80 (sbr, 1H); 3.78 (s, 3H); 4.69 (s, 2H); 6.82-7.33 (m, 8H) MS: 254 (M+), 211, 182, 181, 168, 165, 153, 152.

Sources & evidence

ORD record
ord-71c9ec0b8864452fa2bbe3a5637158e3
Source dataset
uspto-grants-1998_07
Patent number
US05780501

Reaction notes

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