HCID 18663609, compound → HCID 18663608, compound

HRID 1956608Notes

Reaction equation

HRID 1956608 reaction equation
[Br:1][C:2]1[C:12]2[O:11][C:10]3[CH:13]=[CH:14][CH:15]=[CH:16][C:9]=3[CH:8]=[C:7]([C:17](O)=[O:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1>CCCCCC.C(OCC)(=O)C>[Br:1][C:2]1[C:12]2[O:11][C:10]3[CH:13]=[CH:14][CH:15]=[CH:16][C:9]=3[CH:8]=[C:7]([CH2:17][OH:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 18663609HCID 18663609, compound

Product 1

HCID 18663608HCID 18663608, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Preparation analogous to Example 12f) from 6-bromo-dibenz[b,f]oxepine-10-carboxylic acid. Yield: 99% crude, brown oil; TLC (silica gel; hexane/ethyl acetate=7:3; UV): Rf =0.07; 1H-NMR (CDCl3, 200 MHz): 3.54 (s, 2H); 6.70-7.49 (m, 8H).

Sources & evidence

ORD record
ord-aa7cc4d26a3141b5b7d08108b1a0ac1d
Source dataset
uspto-grants-1998_07
Patent number
US05780501

Reaction notes

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