2-Nitrophenyl isocyanate → N-(2-hydroxy-4-nitrophenyl)-N'-(2-nitrophenyl)urea

HRID 1956638ノート

反応式

HRID 1956638 の反応式
[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].[N+:12]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[N:21]=[C:22]=[O:23])([O-:14])=[O:13]>>[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH:4][C:22]([NH:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[N+:12]([O-:14])=[O:13])=[O:23]

参加物

3

反応物 2

HCID 768342-Nitrophenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

生成物 1

HCID 21184705N-(2-hydroxy-4-nitrophenyl)-N'-(2-nitrophenyl)urea収率 44%

実験手順

N-(2-Hydroxy-4-nitrophenyl)-N'-(2-nitro phenyl)urea was prepared from 2-hydroxy 4-nitro aniline (500 mg, 3.24 mmol) and 2-nitro phenyl isocyanate (3.24 mmol) according to the procedure in General Method B. The product was purified by dilution with methylene chloride and precipitation with hexanes. Filtering afforded the title compound(0.44 g, 44%). EI-MS m/z 319(M+H)+

後処理

  1. customThe product was purified by dilution with methylene chloride and precipitation with hexanes
  2. filtrationFiltering

出典と根拠

ORDレコード
ord-3a9008fac8e148efabb41c4781be5656
出典データセット
uspto-grants-1998_07
特許番号
US05780483

反応ノート

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