Chlorophenyl isocyanate → HCID 9883044, compound

HRID 1956652Notes

Reaction equation

HRID 1956652 reaction equation
[N+:1]([C:4]1[CH:10]=[CH:9][C:7]([NH2:8])=[C:6]([OH:11])[CH:5]=1)([O-:3])=[O:2].[Cl:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N:19]=[C:20]=[O:21]>>[OH:11][C:6]1[CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:10]=[CH:9][C:7]=1[NH:8][C:20]([NH:19][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=1[Cl:12])=[O:21]

Participants

3

Reactant 2

HCID 76833Chlorophenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

Product 1

HCID 9883044HCID 9883044, compoundYield 47.1%

Procedure

The urea was prepared from 4-nitro 2-hydroxy aniline(308 mg, 2 mmol) and 2-chloro phenyl isocyanate(2 mmol) by general Method B. It was purified by dilution with methylene chloride and precipitation with hexane. Filtering afforded the title compound(0.29 g, 47%). EI-MS m/z 308(M+H)+

Workup

  1. customIt was purified by dilution with methylene chloride and precipitation with hexane
  2. filtrationFiltering

Sources & evidence

ORD record
ord-45ef1228731f4924b0917858a0c853d1
Source dataset
uspto-grants-1998_07
Patent number
US05780483

Reaction notes

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