Benzenemethanamine, 3,5-dichloro- → HCID 17819382, compound

Participants

Reaction Steps

A mixture of 3-butoxy-4-tert-butylamino-cyclobut-3-ene-1,2-dione (1.13 g, 5 mmol, Example 1), 3.5-dichlorobenzylamine (0.88 g, 5 mmol) and tetrahydrofuran (15 mL) was stirred at room temperature overnight, and then was processed as in Example 2, Step 4. Recrystallization (twice) of the crude product from methanol gave 1.095 g of the title compound as a whte solid: mp 281°-283° C. (dec). MS (m/z) 326/328/330 (M+). HPLC indicates a major component (99.2%).

Provenance & Evidence