2,3-Dichlorobenzylamine → 3-(t-Butylamino)-4-(2,3-dichloro-benzylamino)-cyclobut-3-ene-1,2-dione

Beteiligte Stoffe

Reaktionsschritte

Tetrahydrofuran (12 mL), 3-butoxy-4-tert-butylamino-cyclobut-3-ene-1,2-dione (1.13 g, 5.0 mmol, Example 1), and 2,3-dichlorobenzylamine (0.88 g, 5.0 mmol) were stirred together at room temperature for 64 hours. After removal of solvent, trituation of the residue with diethyl ether and drying gave 1.46 g of a white solid. Four recrystallizations of this crude product from acetonitrile provided 0.927 g of the title compound as a white solid: mp 237°-243° C. (dec). MS (m/z) 327 ([M+H]+).

Herkunft & Nachweise