Hydrogen Bromide → HCID 23203302, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of adipic acid monomethyl ester (8.0 g) in carbon tetrachloride (5 ml) was added thionyl chloride (14.4 ml). The mixture was stirred at 65° C. for 30 minutes. N-Bromosuccinimide (10.7 g), carbon tetrachloride (25 ml) and 48; hydrobromic acid aqueous solution (0.5 ml) was added to the mixture. The mixture was refluxed for 1.5 hours, cooled at room temperature and filtered off. The filtrate was evaporated and distillated at reduced pressure to give methyl 5-bromo-5-chloroformylpentanoate as an oil (9.02 g).

Provenance & Evidence