Benzoyl chloride → HCID 53910362, compound

HRID 1956846Notes

Reaction equation

HRID 1956846 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[N:5]=[CH:6][N:7]([CH2:9][CH2:10][CH2:11][NH:12][C:13]([CH2:22][CH3:23])([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:14][CH3:15])[CH:8]=1.[C:24](Cl)(=[O:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH2:14]([C:13]([NH:12][CH2:11][CH2:10][CH2:9][N:7]1[CH:8]=[C:4]([CH2:3][CH2:2][NH:1][C:24](=[O:31])[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[N:5]=[CH:6]1)([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:22][CH3:23])[CH3:15]

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 183495694-(2-Aminoethyl)-N-(1-ethyl-1-phenylpropyl)-1H-imidazole-1-propanamine

Product 1

HCID 53910362HCID 53910362, compound

Procedure

3-[4-(2-Aminoethyl)imidazol-1-yl]-N-(1-ethyl-1-phenylpropyl)propylamine (1.0 g) was reacted with benzoyl chloride (0.38 ml) in a similar manner to Example 55 to give N-(2-{1-[3-(1-ethyl-1-phenylpropylamino)propyl]imidazol-4-yl}ethyl)benzamide, as an oil.

Sources & evidence

ORD record
ord-c024a5ee8416473e984a12f187a58e1b
Source dataset
uspto-grants-1998_07
Patent number
US05780642

Reaction notes

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