HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 2-[2-(4-Chlorophenyl)-1,3-dioxolan-2-yl]ethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 3,4'-Dichloropropiophenone | HCID 77550 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Solvent | Ethylene Glycol | HCID 174 | — |
| Product | 2-[2-(4-Chlorophenyl)-1,3-dioxolan-2-yl]ethylamine | HCID 18349684 | — |
Reaction Steps
3,4'-Dichloropropiophenone was treated with potassium phthalimide, the product treated with ethylene glycol and then this product cleaved with hydrazine hydrate following the methods described in J. Org. Chem. 1972, 221-225, to give 2-[2-(4-chlorophenyl)-1,3-dioxolan-2-yl]ethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780642 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-ebe6b67134b141b89995484a8022afdf |
| Source note | uspto-grants-1998_07 |