HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(1-ethyl-1-phenylpropyl)acrylamide → 3-[4-(cyanomethyl)imidazol-1-yl]-N-(1-ethyl-1-phenylpropyl)propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(1-ethyl-1-phenylpropyl)acrylamide | HCID 18349645 | — |
| Reactant | HCID 178510863 | HCID 178510863 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3-[4-(cyanomethyl)imidazol-1-yl]-N-(1-ethyl-1-phenylpropyl)propionamide | HCID 22007465 | — |
Reaction Steps
In a similar manner to Example 24, N-(1-ethyl-1-phenylpropyl)acrylamide (6.1 g) and 4-cyanomethylimidazole (3.0 g, Sigma Chemicals) were reacted in 1,4-dioxane (60 ml) in the presence of Triton B (0.8 ml) to give 3-[4-(cyanomethyl)imidazol-1-yl]-N-(1-ethyl-1-phenylpropyl)propionamide, m.p. 121°-122° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780642 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-38e1fe689a62493a8ff7ece1924852d7 |
| Source note | uspto-grants-1998_07 |