HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributylphosphine → 5-(4-{2-[1-(4-Biphenylyl)ethylideneaminooxy]ethoxy}benzyl)-3-trityloxazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributylphosphine | HCID 13831 | — |
| Reactant | 5-(4-Hydroxybenzyl)-3-trityloxazolidine-2,4-dione | HCID 14913662 | — |
| Reactant | 2-[1-(4-Biphenylyl)ethylideneaminooxy]ethanol | HCID 54400349 | — |
| Reactant | 1,1'-(Azodicarbonyl)dipiperazine | HCID 54471820 | — |
| Product | 5-(4-{2-[1-(4-Biphenylyl)ethylideneaminooxy]ethoxy}benzyl)-3-trityloxazolidine-2,4-dione | HCID 86751832 | 50.7% |
Reaction Steps
Following a procedure similar to that described in Example 3(a), but using 0.23 g of 2-[1-(4-biphenylyl)ethylideneaminooxy]ethanol (prepared as described in Preparation 15), 0.40 g of 5-(4-hydroxybenzyl)-3-trityloxazolidine-2,4-dione, 0.40 g of tributylphosphine and 0.50 g of 1,1'-(azodicarbonyl)dipiperazine, 0.31 g of the title compound was obtained as a crystalline powder, melting at 193°-195° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780490 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-afae746c62754cc09e41d39e49fdd175 |
| Source note | uspto-grants-1998_07 |