HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 67675740, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Methyl L-phenylalaninate hydrochloride | HCID 75736 | — |
| Reactant | HCID 67675222 | HCID 67675222 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | HCID 67675740 | HCID 67675740 | — |
Reaction Steps
Coupling of N-(3,5-dimethylbenzoyl)-N-methyl-(D)-phenylalanine (derived from the corresponding methylester described in example 78 by hydrolysis with lithium hydroxide in methanol/water: [a]D =+88° (c=1.0, ethanol)) with (L)-phenylalanine methyl ester hydrochloride according to example 1 followed by hydrolysis of the methyl ester moiety according to example 12 gives N-(3,5-dimethylbenzoyl)-N-methyl-(D)-phenylalanyl-(L)-phenylalanine; FAB-MS m/e 457 (M-H)-.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780498 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-fdc1917da04246bf88078f94deaf0e87 |
| Source note | uspto-grants-1998_07 |