HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 54027428, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | (Methylsulfonyl)acetonitrile | HCID 75283 | — |
| Reactant | 2-Chloro-1-benzyl-1H-indole-3-carboxaldehyde | HCID 10563933 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 54027428 | HCID 54027428 | — |
Reaction Steps
To 1 g of 1-benzyl-2-chloroindole-3-carbaldehyde, dissolved in 25 ml of THF, was added 930 mg of methylsulfonylacetonitril and 1.6 g of triethylamine. After 24 hours another 1 g of methylsulfonylacetonitril and 0.3 g of triethylamine was added, and the mixture was stirred for 6 days. The precipitate was collected by filtration to give (4a). Yield 1.1 g of (4a), m.p. 206° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05783575 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-cc1004b4b6dc41a29a28fd5579771a0c |
| Source note | uspto-grants-1998_07 |