HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 53752279, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | (Methylsulfonyl)acetonitrile | HCID 75283 | — |
| Reactant | 2-Chloro-1-methyl-1H-indole-3-carbaldehyde | HCID 314792 | — |
| Reactant | HCID 86751710 | HCID 86751710 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 53752279 | HCID 53752279 | — |
Reaction Steps
To 1 g of 1-methyl-2-chloroindole-3-carbaldehyde, dissolved in 25 ml of MeOH, was added 820 mg of propan-2-propylsulfonylacetonitril and 1.6 ml of triethylamine. After 24 hours another 300 mg of methylsulfonylacetonitril was added, and the mixture was stirred for 48 hours. The precipitate was collected by filtration to give (6a). Yield 1.13 g of (6a), m.p. 141° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05783575 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-040c323caab7480391c77317f5f8616c |
| Source note | uspto-grants-1998_07 |