反应详情

23 g of 3-chloro-2-(4-chloro-3-hydroxycarbonylphenyl)-5-trifluoromethylpyridine in 23 ml of thionyl chloride were refluxed for 5 hours. The excess thionyl chloride was then removed by distillation. The remaining dark brown oil was used without further purification for the subsequent reaction.

1. customThe excess thionyl chloride was then removed by distillation
2. customThe remaining dark brown oil was used without further purification for the subsequent reaction