Beta-Alanine → HCID 90161888, compound

Participants

Reaction Steps

In a similar manner, the chromophore DNP and β-alanine were coupled to Fmoc-Pro-Lac-pins prepared as described in Example 4. This was cleaved from the pin by reaction with 150 μl of a 50:50 mixture of saturated methylamine in ethanol and water at room temperature for 2.5 hrs to yield DNP-β Ala-Pro-NH-CH3. The solution was evaporated to dryness to remove excess methylamine. FIG. 9b is the HPLC analysis of the cleavage product and again demonstrates that it is of excellent purity.

Provenance & Evidence