HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 86745972, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 86745973 | HCID 86745973 | — |
| Product | HCID 86745972 | HCID 86745972 | — |
Reaction Steps
2-Benzyl-4-isopropyl-6-oxo-tetrahydrosaccharin of preparation 21 is reduced with sodium borohydride and methylated with methyl iodide in the presence of sodium hydride to provide 2-benzyl-4-isopropyl-6-methoxy-tetrahydrosaccharin. This is debenzylated and chloromethylated as in preparation 21 to provide 2-chloromethyl-4-isopropyl-6-methoxy-4,5,6,7-tetrahydrosaccharin.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05783589 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-116a6928ae9d47a1b880500dd94cdb4a |
| Source note | uspto-grants-1998_07 |