Potassium cyanate → HCID 19067935, compound

HRID 1957544Notes

Reaction equation

HRID 1957544 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[C:14]2[C:9](=[C:10]([CH2:19][CH:20]=[CH2:21])[C:11]([OH:18])=[C:12]([CH2:15][CH:16]=[CH2:17])[CH:13]=2)[CH2:8][CH2:7][C:6]1=[O:22].[O-:23][C:24]#[N:25].[K+]>O>[CH2:19]([C:10]1[C:11]([OH:18])=[C:12]([CH2:15][CH:16]=[CH2:17])[CH:13]=[C:14]2[C:9]=1[CH2:8][CH2:7][C:6](=[O:22])[N:5]2[CH2:4][CH2:3][CH2:2][NH:1][C:24]([NH2:25])=[O:23])[CH:20]=[CH2:21]

Participants

4

Reactant 2

HCID 11378442Potassium cyanateHCID 19067902HCID 19067902, compound

Product 1

HCID 19067935HCID 19067935, compoundYield 29%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1.68 Grams of 1-(3-aminopropyl)-5,7-diallyl-3,4-dihydro-6-hydroxy-2(1H)-quinolinone was dissolved in 100 ml of water, then 10 ml of an aqueous solution containing 1 g of potassium cyanate was added thereto under ice-cooling condition, and stirred at room temperature for 12 hours. The crystals thus precipitated were collected by filtration and washed with water, there was obtained 0.5 g (29%) of 5,7-diallyl-3,4-dihydro-6-hydroxy-1-(3-ureidopropyl)-2(1H)-quinolinone.

Workup

  1. additionwas added
  2. temperatureunder ice-cooling condition
  3. customThe crystals thus precipitated
  4. filtrationwere collected by filtration
  5. washwashed with water

Sources & evidence

ORD record
ord-aa25626b302e448db6669d0a51a67de0
Source dataset
uspto-grants-1998_07
Patent number
US05786367

Reaction notes

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