HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 86752952, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 5-(4-Aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine | HCID 15410467 | — |
| Reactant | 4-Chloro-2-methoxybenzoyl chloride | HCID 22142450 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86752952 | HCID 86752952 | — |
Reaction Steps
As described for Example 9, a mixture of 30 0.377 g (1 mmol) of 5-(4-aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine, 0.295 g of 2-methoxy-4-chlorobenzoyl chloride, and 0.15 g of triethylamine in 10 ml of dichloromethane is stirred at room temperature for 3 hours. An additional 0.148 g of 2-methoxy-4-chlorobenzoyl chloride and 75 mg of triethylamine is added and the mixture stirred overnight. The solution is worked-up as for Example 9 to give 0.38 g of product (crystallized from dichloromethane-hexane) m.p. 237°-239° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05786353 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-9bcbb384e2aa42b9b4ae7ff41aed9c40 |
| Source note | uspto-grants-1998_07 |