6,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepine → HCID 86752953, compound

HRID 1957660Notes

Reaction equation

HRID 1957660 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:3]=1[C:4]([NH:6]C1C=CC(C(Cl)=O)=CC=1)=[O:5].[N:21]1[C:31]2[C:30]3[CH:32]=[CH:33][CH:34]=[CH:35][C:29]=3[NH:28][CH2:27][CH2:26][C:25]=2[CH:24]=[N:23][CH:22]=1>N1C=CC=CC=1>[N:21]1[C:31]2[C:30]3[CH:32]=[CH:33][CH:34]=[CH:35][C:29]=3[N:28]([C:4]([C:3]3[CH:16]=[CH:17][C:18]([C:19]4[C:2]([Cl:1])=[C:3]([CH:16]=[C:17]([Cl:20])[CH:18]=4)[C:4]([NH2:6])=[O:5])=[CH:19][CH:2]=3)=[O:5])[CH2:27][CH2:26][C:25]=2[CH:24]=[N:23][CH:22]=1

Participants

4

Reactant 2

HCID 543969886,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepineHCID 545700794-[(2,5-Dichlorobenzoyl)amino]benzoyl chloride

Product 1

HCID 86752953HCID 86752953, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

As described for Example 1, 5 mmol of 4-[(2,5-dichlorobenzoyl)amino]benzoyl chloride is reacted with 5 mmol of 5,6-dihydro-7H-pyrimido-[5,4-d][1]benzazepine in pyridine to give the product as a solid.

Sources & evidence

ORD record
ord-bf42c76af9c74416bd4fc14af68c1c26
Source dataset
uspto-grants-1998_07
Patent number
US05786353

Reaction notes

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