HCID 15377742, compound → HCID 19068241, compound

HRID 1957702Notes

Reaction equation

HRID 1957702 reaction equation
[C:1]12([C:11]3[CH:12]=[C:13]([SH:19])[CH:14]=[CH:15][C:16]=3[O:17][CH3:18])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.Br[CH2:21][C:22]1[S:23][CH:24]=[C:25]([C:27]([O:29][CH3:30])=[O:28])[CH:26]=1>>[C:1]12([C:11]3[CH:12]=[C:13]([S:19][CH2:21][C:22]4[S:23][CH:24]=[C:25]([C:27]([O:29][CH3:30])=[O:28])[CH:26]=4)[CH:14]=[CH:15][C:16]=3[O:17][CH3:18])[CH2:2][CH:3]3[CH2:9][CH:7]([CH2:6][CH:5]([CH2:4]3)[CH2:10]1)[CH2:8]2

Participants

3

Reactant 2

HCID 15377742HCID 15377742, compoundHCID 19068282HCID 19068282, compound

Product 1

HCID 19068241HCID 19068241, compound

Procedure

In a manner analogous to that of Example 17(a), 800 mg (2.9 mmol) of 3-(1-adamantyl)-4-methoxythiophenol were reacted with 690 mg (2.9 mmol) of methyl 2-bromomethyl-4-thiophenecarboxylate and 700 mg (56%) of the expected methyl ester were recovered in the form of a colorless oil.

Workup

  1. customwere recovered in the form of a colorless oil

Sources & evidence

ORD record
ord-142750486cfb440d8d43a033565ec73f
Source dataset
uspto-grants-1998_07
Patent number
US05786379

Reaction notes

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