1-(Chloromethoxy)-2-methoxyethane → HCID 54466392, compound

HRID 1957704Notes

Reaction equation

HRID 1957704 reaction equation
[C:1]12([C:11]3[C:12]([OH:20])=[CH:13][C:14]([OH:19])=[C:15]([CH:18]=3)[CH:16]=[O:17])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH3:21][O:22][CH2:23][CH2:24][O:25][CH2:26]Cl>>[C:1]12([C:11]3[C:12]([O:20][CH2:21][O:22][CH2:23][CH2:24][O:25][CH3:26])=[CH:13][C:14]([O:19][CH2:21][O:22][CH2:23][CH2:24][O:25][CH3:26])=[C:15]([CH:18]=3)[CH:16]=[O:17])[CH2:2][CH:3]3[CH2:9][CH:7]([CH2:6][CH:5]([CH2:4]3)[CH2:10]1)[CH2:8]2

Participants

3

Reactant 2

HCID 775901-(Chloromethoxy)-2-methoxyethaneHCID 19063061HCID 19063061, compound

Product 1

HCID 54466392HCID 54466392, compoundYield 75.2%

Procedure

In a manner analogous to that of Example 17(a), 25 g (91.9 mmol) of 5-(1-adamantyl)-2,4-dihydroxybenzaldehyde were reacted with 26.2 ml (0.23 mol) of 2-methoxyethoxymethyl chloride and 31 g (75%) of the expected compound were recovered in the form of a yellow oil.

Sources & evidence

ORD record
ord-4ee2b3e97f674a90ad79e7fbaf1dff14
Source dataset
uspto-grants-1998_07
Patent number
US05786379

Reaction notes

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