2-Naphthalenecarboxaldehyde → HCID 22876505, compound

HRID 1957735Notes

Reaction equation

HRID 1957735 reaction equation
[CH:1]1[CH:6]=[CH:5][C:4]([CH:7]([NH2:10])[CH2:8][OH:9])=[CH:3][CH:2]=1.[CH:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][C:12]=1[CH:21]=O>>[CH:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][C:12]=1[CH2:21][NH:10][C@H:7]([C:4]1[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=1)[CH2:8][OH:9]

Participants

3

Reactant 2

HCID 62012-NaphthalenecarboxaldehydeHCID 924662-Amino-2-phenylethanol

Product 1

HCID 22876505HCID 22876505, compound

Procedure

Using 1.00 g (7.29 mmol) of (R)-phenylglycinol ((R)-VIII-2) and β-naphthoaldehyde, a similar operation was carried out to obtain (R)-N-(β-naphthyl)methyl-2-phenylglycinol (2.01 g) ((R)-II-3) quantitatively. ##STR318##

Sources & evidence

ORD record
ord-97c692854b9e418ca3f7732aeb235ebf
Source dataset
uspto-grants-1998_07
Patent number
US05786485

Reaction notes

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