反应详情

3-methylsulfonylamino-5-nitro-benzoic acid methyl ester (32 g; 0.12 mol) was suspended in methanol (500 ml), 4 g (5% w/w; 4 g) was added and the mixture was hydrogenated at 4-5 bar. The reaction mixture was subsequently filtered on a Celite pad and the filtrate concentrated. 23 g (0.08 mmol; 66% yield) of a yellow powder were obtained.

1. addition4 g (5% w/w; 4 g) was added
2. filtrationThe reaction mixture was subsequently filtered on a Celite pad
3. concentrationthe filtrate concentrated
4. custom23 g (0.08 mmol; 66% yield) of a yellow powder were obtained