反应详情

1-Methylsulfonyl-3-methoxy-5-nitro-benzene (1.3 g; 5.6 mmol) was dissolved in methanol (40 ml) and 80 mg Pd/C (5% w/w) were added and the reaction mixture was hydrogenated at 2 bar. The mixture was then diluted with dichloromethane, filtrated above over a celite pad, concentrated and the residual was crystallized from methanol. 0.5 g (2.48 mmol; 44% yield) of a solid were obtained.

1. filtrationfiltrated above over a celite pad
2. concentrationconcentrated
3. customthe residual was crystallized from methanol
4. custom0.5 g (2.48 mmol; 44% yield) of a solid were obtained