HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → Methyl N-cyano-2-methylmorpholine-4-carbimidothioate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Dimethyl N-cyanodithioiminocarbonate | HCID 66289 | — |
| Reactant | 2-Methylmorpholine--hydrogen chloride (1/1) | HCID 22605557 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Methyl N-cyano-2-methylmorpholine-4-carbimidothioate | HCID 80489835 | 63.4% |
Reaction Steps
A mixture of 2-methylmorpholine hydrochloride (1.0 g, 9.9 mmol), dimethyl cyanocarbonimidodithioate (1.45 g, 9.9 mmol) and sodium carbonate (0.2 g, 1.9 mmol) in ethanol (50 mL) was stirred at ambient temperature overnight. The reaction mixture was concentrated and purified through silica gel chromatography to give the desired product (1.25 g, 63%). LC-MS: 200 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410095B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-59e310a4c4df43d89511b21394ac8827 |
| Source note | uspto-grants-2013_04 |