4-Chlorophenylboronic acid → HCID 67280517, compound

HRID 1958100Notes

Reaction equation

HRID 1958100 reaction equation
Br[C:2]1[CH:3]=[C:4]([NH2:13])[CH:5]=[N:6][C:7]=1[O:8][CH2:9][CH:10]1[CH2:12][CH2:11]1.[Cl:14][C:15]1[CH:20]=[CH:19][C:18](B(O)O)=[CH:17][CH:16]=1>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([C:2]2[CH:3]=[C:4]([NH2:13])[CH:5]=[N:6][C:7]=2[O:8][CH2:9][CH:10]2[CH2:12][CH2:11]2)=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 742994-Chlorophenylboronic acidHCID 672819095-Bromo-6-(cyclopropylmethoxy)-3-pyridinamine

Product 1

HCID 67280517HCID 67280517, compound

Procedure

The title compound was synthesized in analogy to Example E, using 5-bromo-6-cyclopropylmethoxy-pyridin-3-ylamine and 4-chlorophenylboronic acid (44%). MS (LC/MS): 275.2 (M+H).

Sources & evidence

ORD record
ord-bc86cf546430461ea7006b9ab1611e5f
Source dataset
uspto-grants-2013_04
Patent number
US08410107B2

Reaction notes

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