Pyridazine-3-carboxylic acid → HCID 56961505, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH2:20])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:19])([F:18])[F:17])=[CH:4][CH:3]=1.[N:21]1[CH:26]=[CH:25][CH:24]=[C:23]([C:27](O)=[O:28])[N:22]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[C:10]([NH:20][C:27]([C:23]3[N:22]=[N:21][CH:26]=[CH:25][CH:24]=3)=[O:28])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])=[CH:6][CH:7]=1Participants
3
Procedure
The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2, 2-trifluoro-ethoxy)-pyridin-3-ylamine and 3-pyridazinecarboxylic acid as starting materials, MS (LC/MS): 409.0 (M+H).
Sources & evidence
- ORD record
- ord-c192c823b3794f4c9cd6773c1f396d40
- Source dataset
- uspto-grants-2013_04
- Patent number
- US08410107B2
Reaction notes
Loading…