1-methyl-1H-pyrazole-5-carboxylic acid → HCID 56961551, compound

HRID 1958121Notes

Reaction equation

HRID 1958121 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH2:20])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:19])([F:18])[F:17])=[CH:4][CH:3]=1.[CH3:21][N:22]1[C:26]([C:27](O)=[O:28])=[CH:25][CH:24]=[N:23]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[C:10]([NH:20][C:27]([C:26]3[N:22]([CH3:21])[N:23]=[CH:24][CH:25]=3)=[O:28])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6431581-methyl-1H-pyrazole-5-carboxylic acidHCID 672813155-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine

Product 1

HCID 56961551HCID 56961551, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2, 2-trifluoro-ethoxy)-pyridin-3-ylamine and 1-methyl-1H-pyrazole-5-carboxylic acid, as starting materials, MS (LC/MS): 409.2 (M−H).

Sources & evidence

ORD record
ord-698c72d7843e4246b014c9b2fca693a2
Source dataset
uspto-grants-2013_04
Patent number
US08410107B2

Reaction notes

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