Dimethyl-1,3-oxazole-5-carboxylic acid → HCID 56961552, compound

HRID 1958122Notes

Reaction equation

HRID 1958122 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH2:20])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:19])([F:18])[F:17])=[CH:4][CH:3]=1.[CH3:21][C:22]1[O:23][C:24]([C:28](O)=[O:29])=[C:25]([CH3:27])[N:26]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[C:10]([NH:20][C:28]([C:24]3[O:23][C:22]([CH3:21])=[N:26][C:25]=3[CH3:27])=[O:29])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 1132979Dimethyl-1,3-oxazole-5-carboxylic acidHCID 672813155-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine

Product 1

HCID 56961552HCID 56961552, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2, 2-trifluoro-ethoxy)-pyridin-3-ylamine and 2,4-dimethyl-5-oxazolecarboxylic acid, as starting materials, MS (LC/MS): 426.2 (M+H).

Sources & evidence

ORD record
ord-44bbda7a2f5c463482db12752f9e660c
Source dataset
uspto-grants-2013_04
Patent number
US08410107B2

Reaction notes

Loading…