5-methyl-1H-pyrazole-3-carboxylic acid → HCID 56961554, compound

HRID 1958124Notes

Reaction equation

HRID 1958124 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH2:20])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:19])([F:18])[F:17])=[CH:4][CH:3]=1.[CH3:21][C:22]1[NH:26][N:25]=[C:24]([C:27](O)=[O:28])[CH:23]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[C:10]([NH:20][C:27]([C:24]3[CH:23]=[C:22]([CH3:21])[NH:26][N:25]=3)=[O:28])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 98225-methyl-1H-pyrazole-3-carboxylic acidHCID 672813155-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine

Product 1

HCID 56961554HCID 56961554, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2, 2-trifluoro-ethoxy)-pyridin-3-ylamine and 5-methyl-1H-pyrazole-3-carboxylic acid as starting materials, MS (LC/MS): 409.2 (M−H).

Sources & evidence

ORD record
ord-f2ac544df24e48cab709053ba49ff142
Source dataset
uspto-grants-2013_04
Patent number
US08410107B2

Reaction notes

Loading…