4-Methyl-1,2,3-thiadiazole-5-carboxylic acid → HCID 56961605, compound

HRID 1958128Notes

Reaction equation

HRID 1958128 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH2:20])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:19])([F:18])[F:17])=[CH:4][CH:3]=1.[CH3:21][C:22]1[N:23]=[N:24][S:25][C:26]=1[C:27](O)=[O:28]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[C:10]([NH:20][C:27]([C:26]3[S:25][N:24]=[N:23][C:22]=3[CH3:21])=[O:28])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 13819924-Methyl-1,2,3-thiadiazole-5-carboxylic acidHCID 672813155-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine

Product 1

HCID 56961605HCID 56961605, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2, 2-trifluoro-ethoxy)-pyridin-3-ylamine and 4-methyl-1,2,3-thiadiazole-5-carboxylic acid, as starting materials, MS (LC/MS): 429.2 (M+H).

Sources & evidence

ORD record
ord-1df89da2a61f4b1d89cbfa7fc85cec02
Source dataset
uspto-grants-2013_04
Patent number
US08410107B2

Reaction notes

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