HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methylnicotinic acid → N-[5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-6-methyl-3-pyridinecarboxylic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methylnicotinic acid | HCID 137860 | — |
| Reactant | 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine | HCID 67281315 | — |
| Product | N-[5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-6-methyl-3-pyridinecarboxylic acid amide | HCID 56961606 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2, 2-trifluoro-ethoxy)-pyridin-3-ylamine and 6-methyl-3-pyridinecarboxylic acid as starting materials, MS (LC/MS): 420.4 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-8c9f1483419f41ba90e8b9083848a194 |
| Source note | uspto-grants-2013_04 |