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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1958137Generated: November 1, 2026

3-Methylpicolinic acid → 3-Methyl-2-pyridinecarboxylic acid[5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-amide

https://huagongshe.com/reaction/1958137

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methylpicolinic acidHCID 268757—
Reactant5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamineHCID 67281315—
Product3-Methyl-2-pyridinecarboxylic acid[5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-amideHCID 56961663—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2, 2-trifluoro-ethoxy)-pyridin-3-ylamine and 3-methyl-2-pyridinecarboxylic acid as starting materials, MS (LC/MS): 422.0 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08410107B2
Source datasetuspto-grants-2013_04
ORD IDord-ce19db8b77bc4157a3e15d7a713b3000
Source noteuspto-grants-2013_04