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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1958138Generated: October 26, 2026

5-methyl-1,3-oxazole-4-carboxylic Acid → 5-Methyl-4-oxazolecarboxylic acid[5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-amide

https://huagongshe.com/reaction/1958138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-methyl-1,3-oxazole-4-carboxylic AcidHCID 11355484—
Reactant5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamineHCID 67281315—
Product5-Methyl-4-oxazolecarboxylic acid[5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-amideHCID 56961283—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2, 2-trifluoro-ethoxy)-pyridin-3-ylamine and 5-methyl-4-oxazolecarboxylic acid as starting materials, MS (LC/MS): 412.2 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08410107B2
Source datasetuspto-grants-2013_04
ORD IDord-638e72251a7f47a1902a81428706d2d2
Source noteuspto-grants-2013_04